Effect of subcutaneous injection of mono-sodium glutamate on some nutritional and biochemical traits in albino rats

Mono-sodium glutamate [MSG] was administered sub-cutaneously to female rats 113.4 +/- 1.97 g body weight, as a food flavors at doses of 0.4, 0.8 and 1.2 mg per g body weight for 6-week period. MSG were significantly decreased body weight [26.5, 31.04 and 31.61%] and significantly increased feed consumption [22.92, 32.18 and 32.61%] and efficiency of feed utilization [60.44, 70.25 and 73.2%] for treated groups, respectively. No significant changes in weight of ovaries and spleen were shown. On the other h and, adrenal glands were significantly decreased, but weight of brain, heart, uterus, kidney, and liver were significantly increased in rats treated with MSG. Levels of blood glucose, urea, ceratinine, cholesterol, total protein, alkaline phosphatase, AST, and ALT were significantly increased in rat groups received MSG, while serum albumin was increased [nonsignificantly]. In conclusion, MSG may have a direct effect on functions of kidneys, liver and may inter adversely in carbohydrates, lipids, and proteins metabolism

Effect of aspirin on nutritional parameters, plasma proteins and blood haemoglobin in growing rats

The effect of low and high doses of aspirin [50 and 150 mg/kg rat body weight] on protein efficiency ratio, blood hemoglobin, percentage hematocrit and plasma proteins were studied in growing rats fed balanced diet. Results showed that protein efficiency ratio of rats given the high dose was significantly decreased. Blood hemoglobin increased significantly when aspirin was given. Hematocrit was affected significantly by aspirin treatment. Plasma total protein and globulin increased significantly. Albumin/globulin ratio decreased significantly on administration of both aspirin doses